Omed: Use in Patients with Impaired Liver Function: Dosage reduction may be required in patients with impaired liver function as Omeprazole is extensively metabolized in the liver and its elimination rate is prolonged in such patients when compared to normal persons. The daily dose of 10-20 mg is recommended in patients with severe liver disease.
Use In Patients with Impaired Kidney Function: It is not necessary to adjust the dose of omeprazole in patients with renal insufficiency.
Use in Pregnancy and Lactation: There is no adequate data on the safety of Omeprazole in pregnant women. Animal studies have revealed no teratogenic effect, but reproduction studies have revealed reduced lifter weights. However, to avoid the risk of developing the undesirable effects, Omeprazole should not be recommended in pregnancy unless its use is essential.
It is not known whether Omeprazole is secreted into human milk. Breast feeding should therefore be discontinued if the use of Omeprazole is considered essential.
Use in Children: The safety and effectiveness of Omeprazole Sodium Injection in children have not been established.
Use in Elderly: It is not necessary to adjust the dose of Omeprazole in elderly patients. However, a slight decrease in elimination rate and an increase in bioavailability are likely to occur in such patients.