Omexac-20: Adults: Oral.
GERD or erosive esophagitis: 20 mg/day for 4-8 weeks.
Pathologically hypersecretory conditions: 60 mg once daily to start; doses up to 120 mg 3 times/day have been administered; administered daily doses >80 mg in divided doses.
Helicobacter pylori: combination therapy with bismuth subsalicylate, tetracycline, and clarithromycin; or with clarithromycin alone.
Adult dose: Oral: 20 mg twice daily.
Gastric ulcers: 40 mg/day for 4-8 weeks, or as prescribed by the physician.
Omexac-40: Alternative to oral therapy: In patients where the use of oral medicinal products is inappropriate, Omeprazole 40 mg IV once daily is recommended. In patients with Zollinger-Ellison syndrome the recommended initial dose of Omeprazole given intravenously is 60 mg daily. Higher daily doses may be required and the dose should be adjusted individually. When doses exceeds 60 mg daily, the dose should be divided and given twice daily. Omeprazole solution for injection must be given only as an intravenous injection and it must not be added to infusion solutions. After reconstitution the injection should be given slowly over a period of at least 2.5 minutes at a maximum rate of 4 mL per minute. Or as prescribed by the physician.
Special Population: Impaired renal function: Dose adjustment is not needed in patients with impaired renal function.
Impaired hepatic function: In patients with impaired hepatic function a daily dose of 10-20 mg may be sufficient.
Elderly (>65 years old): Dose adjustment is not needed in the elderly.
Pediatric patients: There is limited experience with Omeprazole for intravenous use in children.