Legency Remedies


Concise Prescribing Info
Salbutamol sulfate
Management of reversible airways obstruction, as in asthma & in some patients w/ COPD.
Dosage/Direction for Use
Adult Initially 2.5 mg as a single dose. May be increased to 5 mg & repeated up to qid. Childn ≥12 yr Adult dose, 4-11 yr 2.5-5 mg up to qid.
Hypersensitivity. Do not use for the management of premature labour; in threatened abortion.
Special Precautions
Do not inj or swallow. Not to be the only or main treatment in patients w/ severe or unstable asthma; consider using max recommended dose of inhaled corticosteroid &/or oral corticosteroid therapy. Assess & consider increasing anti-inflammatory therapy (eg, higher doses of inhaled or oral corticosteroid) if short-acting relief bronchodilator treatment becomes less effective or more inhalations than usual are required. Severe exacerbations of asthma must be treated in the normal way. Thyrotoxicosis. Patients w/ underlying severe heart disease (eg, ischaemic heart disease, arrhythmia or severe heart failure) should seek medical advice if chest pain or other symptoms of worsening heart disease is experienced. Patients known to have received large doses of other sympathomimetic drugs. Potentially serious hypokalaemia in acute severe asthma due to hypoxia & concomitant use w/ xanthine derivatives, steroids & diuretics. Monitor K levels; development of elevated serum lactate & consequent metabolic acidosis. Diabetic patients. Combination w/ nebulised anticholinergics. Paradoxical bronchospasm may occur w/ an immediate increase in wheezing after dosing. Pregnancy & lactation.
Adverse Reactions
Fine tremor of skeletal muscle (particularly the hands), palpitations, tachycardia, nervous tension, headaches, peripheral vasodilatation, & rarely muscle cramps. Potentially serious hypokalaemia after large doses; myocardial ischaemia; hypersensitivity reactions including paradoxical bronchospasm, angioedema, urticaria, hypotension, & collapse.
Drug Interactions
Increased risk of hypokalaemia w/ corticosteroids, diuretics, or xanthines.
MIMS Class
Antiasthmatic & COPD Preparations
ATC Classification
R03AC02 - salbutamol ; Belongs to the class of adrenergic inhalants, selective beta-2-adrenoreceptor agonists. Used in the treatment of obstructive airway diseases.
Oppul soln for inhalation 1 mg/mL
2.5 mL x 25 × 1's;2.5 mL x 30 × 1's
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