Theon Pharma


Cathay Drug
Concise Prescribing Info
Pantoprazole Na sesquihydrate 40 mg, domperidone 30 mg
Management of GERD; gastritis, non-ulcer dyspepsia, gastric or duodenal ulcer, dyspepsia, bloating, fullness, belching, NSAID-induced dyspepsia.
Dosage/Direction for Use
Should be taken on an empty stomach: Take 30-60 min before breakfast. Take at around the same time every day. Swallow whole, do not chew.
Hypersensitivity. Pregnancy & lactation.
Special Precautions
Lactation. Pantoprazole: Not recommended in childn <12 yr. Long term therapy may lead to bacterial overgrowth in GIT. Domperidone: Increases serum prolactin levels resulting to galactorrhoea in females & gynaecomastia in males.
Adverse Reactions
Rash, pruritus. Pantoprazole: Diarrhoea, dizziness, GIT infections; anaphylaxis, angioedema, chest pain, dyspnea, erythema multiforme, gastroenteritis, hyperglycaemia, infection, jaundice, optic neuropathy, anterior ischaemia, pancreatitis, speech disorder. Domperidone: Headache, insomnia, nervousness, dizziness, thirst, lethargy, irritability, GP disturbances, hot flushes, mastalgia, galactorrhoea, gynecomastia, menstrual irregularities, urticaria, stomatitis, conjunctivitis, urinary frequency, dysuria, oedema, palpitations, leg cramps, asthaenia, drug intolerance.
Drug Interactions
Pantoprazole: May interfere w/ absorption of ketoconazole, ampicillin esters & Fe salts. Domperidone: Decreased anti-dyspeptic effects w/ anti-cholinergic drugs. Decrease effect w/ antimuscarinic agents & opioid analgesics. Suppressed peripheral effects of dopaminergic agonists. Gastrokinetic effects could influence the absorption SR or EC formulations. Interference w/ serum prolactin levels may interfere w/ other hypoprolactinaemic agents & w/ some diagnostic tests. Decreased oral bioavailability w/ antacids & anti-secretory agents. Food. Decreased oral bioavailability of cimetidine or Na carbonate.
MIMS Class
Antacids, Antireflux Agents & Antiulcerants
ATC Classification
A02BC02 - pantoprazole ; Belongs to the class of proton pump inhibitors. Used in the treatment of peptic ulcer and gastro-oesophageal reflux disease (GERD).
Pantomide MR cap
30's (P1,050/box)
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