Frequency of >2%: Headache, diarrhea, nausea, abdominal pain, vomiting, flatulence, dizziness, arthralgia.
Frequency of <2%: Body as a Whole:
allergic reaction, fever, photosensitivity reaction, facial edema, thrombophlebitis (I.V. only).
Constipation, dry mouth, hepatitis hematologic, leukopenia (reported in ex-US clinical trials only), thrombocytopenia.
Elevated CPK (creatinine phosphokinase), generalized edema, elevated triglycerides, liver function tests abnormal.
Skin and Appendages:
Urticarial, rash, pruritus.
Post Marketing Experience: General Disorders and Administration Conditions:
asthenia, fatigue, malaise.
Immune System Disorders:
anaphylaxis (including anaphylactic shock).
Skin and Subcutaneous Tissue Disorders:
severe dermatologic reactions (some fatal), including erythema multiforme. Steven-Johnson syndrome, and toxic epidermal necrolysis (TEN), and angioedema (Quincke's edema).
rhabdomyolysis, bone fracture.
Renal and Urinary Disorders:
hepatocellular damage leading to jaundice and hepatic failure.
hallucinations, confusions, insomnia, somnolence.
Metabolism and Nutritional Disorders:
Infections and infestations: Clostridium difficile