Panvell Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Pantoprazole

Indications/Uses

Reflux esophagitis, gastric & duodenal ulcer, Zollinger-Ellison syndrome & other pathological hypersecretory conditions.

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Dosage/Direction for Use

IV Reflux esophagitis, gastric & duodenal ulcer 40 mg/day. Zollinger-Ellison syndrome & other pathological hypersecretory conditions Initially, 80 mg/day, can be titrated as needed. Severe liver impairment Max: 20 mg/day.

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Overdosage

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Contraindications

Hypersensitivity to pantoprazole or substituted benzimidazoles.

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Special Precautions

Monitor liver enzymes in long-term use. Concomitant use w/ atazanavir; vit B₁₂. Increased risk of GI infections caused by Salmonella & Campylobacter or C. difficile. Monitor prothrombin time in concomitant use w/ phenprocoumon or warfarin. Risk of severe hypomagnesaemia; hip, wrist & spine fractures in older people w/ long term use (>1 yr). Pregnancy & lactation. Childn ≤18 yr.

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Use In Pregnancy & Lactation

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Adverse Reactions

Benign fundic gland polyps, increased liver enzymes (transaminases, γ-GT).

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Drug Interactions

May reduce absorption of drugs w/ a gastric pH-dependent bioavailability eg, azole antifungals (ketoconazole, itraconazole, posaconazole) & erlotinib. Substantial reduction in the bioavailability of HIV medications eg, atazanavir. Increased levels of methotrexate (at high dose eg, 300 mg). May reduce absorption of vit B₁₂. Monitor prothrombin time/INR in patients treated w/ coumarin anticoagulants eg, phenprocoumon, warfarin.

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Storage

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Description

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Action

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MIMS Class

Antacids, Antireflux Agents & Antiulcerants

ATC Classification

A02BC02 - pantoprazole ; Belongs to the class of proton pump inhibitors. Used in the treatment of peptic ulcer and gastro-oesophageal reflux disease (GERD).

Regulatory Classification

Presentation/Packing

Form

Panvell powd for inj 40 mg

Packing/Price

1's

Panvell

pantoprazole

Manufacturer:

PT Novell

Distributor:

Prosweal Healthcare