paracetamol + orphenadrine


XL Lab


Macropharma Corp
Concise Prescribing Info
Paracetamol 650 mg, orphenadrine citrate 35 mg
Short-term treatment of moderate pain, particularly after surgery, & for fever. Relieves pain due to skeletal muscle spasm & w/ the paracetamol used in the treatment of musculoskeletal & joint disorders.
Dosage/Direction for Use
Special Precautions
Impaired kidney or liver function; alcohol dependence; cardiac failure, coronary insufficiency, cardiac arrhythmias & tachycardia. Pregnancy & lactation.
Adverse Reactions
Haematological reactions; skin rashes & other hypersensitivity reactions; dryness of mouth, difficulty in swallowing & talking, thirst, reduced bronchial secretions, dilation of the pupils w/ loss of accommodation & photophobia, flushing & dryness of skin, transient bradycardia followed by tachycardia w/ palpitation & arrhythmias & difficulty in micturition, reduction in the tone & motility of the GIT leading to constipation.
Drug Interactions
Increased risk of paracetamol toxicity w/ potentially hepatotoxic drugs or drugs that induce liver microsomal enzymes. Accelerated absorption of paracetamol w/ metoclopramide. Affected excretion & altered plasma conc w/ probenecid. Reduced absorption w/ colestyramine. Caution when used w/ bupropion.
MIMS Class
Analgesics (Non-Opioid) & Antipyretics / Muscle Relaxants
ATC Classification
M03BC51 - orphenadrine, combinations ; Belongs to the class of ethers. Used as centrally-acting muscle relaxants.
Parophen FC tab
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