Pfizer Dobutamine HCl in 5% Dextrose Solution

Pfizer Dobutamine HCl in 5% Dextrose Solution

dobutamine

Manufacturer:

Hospira

Distributor:

Pfizer
Concise Prescribing Info
Contents
Dobutamine HCl in 5% dextrose soln
Indications/Uses
Inotropic support in short-term treatment of adult w/ cardiac decompensation due to depressed contractility resulting either from organic heart disease or cardiac surgical procedures.
Dosage/Direction for Use
Start at a low rate of 0.5-1 mcg/kg/min & titrated at intervals of a few min guided by the patient's response. Optimal infusion rate: 2-20 mcg/kg/min. Max: 40 mcg/kg/min.
Contraindications
Special Precautions
Sulfite sensitivity especially in patient w/ asthma. Continuously monitor ECG, BP, pulmonary wedge pressure, cardiac output & serum K. Avoid bolus administration. Hypovolemia should be corrected prior to use. Concomitant use w/ β-blockers. Marked mechanical obstruction eg, severe valvular aortic stenosis; hypokalemia; known subclinical or overt DM. Do not add to alkaline soln eg, Na bicarbonate. Pregnancy. Childn & elderly.
Adverse Reactions
Marked increased heart rate, BP (especially systolic pressure) & ventricular ectopic activity. Hypotension; phlebitis. Nausea, headache, anginal pain, nonspecific chest pain, palpitations & shortness of breath.
Drug Interactions
β-blockers, nitroprusside.
MIMS Class
Cardiac Drugs
ATC Classification
C01CA07 - dobutamine ; Belongs to the class of adrenergic and dopaminergic cardiac stimulants excluding glycosides. Used in the treatment of hypotension.
Presentation/Packing
Form
Pfizer Dobutamine HCl in 5% Dextrose Solution infusion 1,000 mcg/mL
Packing/Price
(bag) 250 mL x 1's
Form
Pfizer Dobutamine HCl in 5% Dextrose Solution infusion 2,000 mcg/mL
Packing/Price
250 mL x 1's
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