Endocrine disorders: Primary & secondary adrenocortical insufficiency, acute adrenocortical insufficiency, congenital adrenal hyperplasia, hypercalcemia associated w/ cancer, pre-op & in the event of serious trauma or illness, patients w/ known adrenal insufficiency or when adrenocortical reserve is doubtful, nonsuppurative thyroiditis. Rheumatic disorders: Adjunctive therapy for short-term administration in post-traumatic OA, RA including juvenile RA, ankylosing spondylitis, acute nonspecific tenosynovitis, psoriatic arthritis, temporal arthritis, synovitis or OA, acute & subacute bursitis, acute gouty arthritis, epicondylitis. Collagen disorders: During exacerbation or maintenance therapy in cases of SLE, systemic dermatomyositis, acute rheumatic carditis. Dermatologic disorders: Pemphigus, Stevens-Johnson syndrome, bullous dermatitis herpetiformis, mycosis fungoides, severe psoriais, exfoliative dermatitis, severe seborrheic dermatitis. Allergic states: Control of severe or incapacitating allergic conditions intractable to adequate trials of conventional treatment in adults & childn w/ bronchial asthma, contact dermatitis, serum sickness, urticarial transfusion reactions, acute noninfectious laryngeal edema, seasonal or perennial allergic rhinitis, atopic dermatitis, drug hypersensitivity reactions. Ophth diseases: Severe acute & chronic allergic & anti-inflammatory processes involving the eye & its adnexa eg, herpes zoster ophthalmicus, chorioretinitis, optic neuritis, anterior segment inflammation, keratitis, ritis, iridocyclitis, diffuse posterior uveitis & choroiditis, sympathetic ophthalmis, allergic conjunctivitis, allergic corneal marginal ulcers. GI diseases: Ulcerative colitis (systemic therapy), Crohn's disease, regional enteritis (systemic therapy). Resp diseases: Symptomatic sarcoidosis, fulminating or disseminated pulmonary TB when used concurrently w/ appropriate anti-TB chemotherapy, Loeffler's syndrome not manageable by other means, aspiration pneumonitis, idiopathic eosinophilic pneumonias, berylliosis, aspirations of gastric contents. Hematologic disorders: Idiopathic thrombocytopenic purpura in adults (IV only, IM administration is CI), erythroblastopenia (RBC anemia, pure red cell aplasia), selected cases of secondary thrombocytopenia in adults, acquired (autoimmune) hemolytic anemia, congenital (erythroid) hypoplastic anemia, aspirations of gastric contents, idiopathic eosinophilic pneumonias. Neoplastic disease: Palliative management of acute leukemia in childn, leukemias & lymphomas in adults. Edematous states/renal diseases: Induce diuresis or remission or proteinuria in nephrotic syndrome, w/o uremia, idiopathic type or due to lupus erythematosus. Nervous system disorders: Acute exacerbations of multiple sclerosis. Medical emergencies: Shock secondary adrenocortical insufficiency or shock unresponsive to conventional therapy when adrenocortical insufficiency may be present, acute allergic disorders following epinephrine. TB meningitis w/ subarachnoid block or impending block when used concurrently w/ appropriate anti-TB chemotherapy, trichinosis w/ neurologic or myocardial involvement.