Albumin (Human) 20% is administered intravenously. The total dosage will vary with the individual. In adults, an initial infusion of 100 mL is suggested. Additional amounts may be administered as clinically indicated. The initial dosage in children will vary with the clinical state and body weight. A dose one-quarter to one half the adult dose may be administered, or dosage may be calculated on the basis of 1-3 mL per kg of body weight. For infants suffering from hemolytic disease of the newborn the appropriate dose for binding the exchange bilirubin is 1 gram per kilogram of body weight. This may be administered before or during the exchange procedure. In the treatment of the patient in shock with greatly reduced blood volume, Human Albumin 20% may be administered as rapidly as necessary in order to improve the clinical condition and restore normal blood volume. This may be repeated in 15-30 minutes if the initial dose fails to prove adequate. In the patient with as slightly low or normal blood volume, the rate of administration should be 1 mL per minute. The usual rate of administration in children should be one-quarter the adult rate.
Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration whenever solution container permits.