Solutions of Albumin 20% should not be used if they appear turbid or if there is sediment in the bottle. Use immediately after opening. Discard unused portion. Human Albumin 20% should be administered with caution to patients with low cardiac reserve. Rapid infusion may cause vascular overload with resultant pulmonary edema. Patients should be closely monitored for signs of increased venous pressure.
A rapid rise in blood pressure following infusion necessitates careful observation of injured or postoperative patients to detect and treat severed blood vessels that may have blend at a lower pressure.
Patients with marked dehydration require administration of additional fluids: Human Albumin 20% may be administered with the usual dextrose and saline intravenous solutions. However, certain solutions containing protein hydrolyses or alcohol must not be infused through the same administration set in conjunction with Human Albumin 20% since these combinations may cause the proteins to precipitate.
Pregnancy category C: Animal reproduction studies have not been conducted with Albumin (Human). It is also not known whether Albumin (Human) can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Albumin (Human) should be given to a pregnant woman only if clearly needed.