Plendil ER

Plendil ER

felodipine

Manufacturer:

AstraZeneca

Distributor:

Zuellig
Concise Prescribing Info
Contents
Felodipine
Indications/Uses
Dosage/Direction for Use
HTN Initially 5 mg once daily. Maintenance: 5-10 mg once daily. Elderly Initially 2.5 mg daily. Angina pectoris Initially 5 mg once daily, increasing to 10 mg once daily if needed.
Administration
May be taken with or without food: Take tab in the morning. Swallow whole, do not divide/crush/chew. May be taken w/o food or following a light meal not rich in fat or carbohydrates.
Contraindications
Hypersensitivity. Uncompensated heart failure, acute MI, unstable angina pectoris. Pregnancy.
Special Precautions
Rarely, may precipitate significant hypotension in susceptible individuals which may result in MI. Pregnancy & Lactation.
Adverse Reactions
Drug Interactions
Increased plasma conc w/ CYP450 3A4 inhibitors (eg, cimetidine, erythromycin, itraconazole, ketoconazole & certain flavonoids present in grapefruit juice. Decreased plasma conc w/ CYP450 3A4 inducers (eg, phenytoin, carbamazepine, rifampicin, barbiturates). Increases conc of tacrolimus.
ATC Classification
C08CA02 - felodipine ; Belongs to the class of dihydropyridine derivative selective calcium-channel blockers with mainly vascular effects. Used in the treatment of cardiovascular diseases.
Presentation/Packing
Form
Plendil ER tab 10 mg
Packing/Price
30's
Form
Plendil ER tab 2.5 mg
Packing/Price
30's
Form
Plendil ER tab 5 mg
Packing/Price
30's
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