Monitor for any anginal symptoms such as chest pain. Asymptomatic cerebral infarction. Concomitant use with anticoagulants, antiplatelet and thrombolytic drugs or prostaglandin E1 or its derivatives. Risk of hemorrhagia during menstruation; bleeding tendency or predisposition; severe hepatic or renal impairment; coronary artery stenosis; diabetes mellitus or abnormal glucose tolerance; malignant hypertension. Discontinue use or reduce dose if excessive increase in pulse rate is observed in patients with coronary artery stenosis. Long-term use in patients without congestive heart failure. Lactation. Children. Elderly.