Pletaxol

Pletaxol Mechanism of Action

cilostazol

Manufacturer:

Lloyd

Distributor:

InnoGen Pharmaceuticals
Full Prescribing Info
Action
Pharmacology: Pharmacokinetics: Cilostazol is absorbed after oral doses and absorption is increased if taken with a high fat meal. Cilostazol is extensively metabolised in the liver by cytochrome P450 isoenzymes, mainly CYP3A4 and to a lesser extent CYP2C19, to both active and inactive metabolites; these are predominantly excreted in the urine (74%) with the remainder in the faeces (20%). The active metabolites have apparent elimination half-lives of 11 to 13 hours. Cilostazol is 95 to 98% protein bound.
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