Positate

Positate

potassium citrate

Manufacturer:

Cooper Pharma

Distributor:

Macropharma Corp
Concise Prescribing Info
Contents
K citrate
Indications/Uses
Renal tubular acidosis (RTA) w/ Ca stones, hypocitraturic Ca oxalate nephrolithiasis of any etiology & uric acid lithiasis w/ or w/o Ca stones.
Dosage/Direction for Use
Severe hypocitraturia (urinary citrate of <150 mg/day) 60 mEq/day (20 mEq tid or 15 mEq qid). Mild moderate hypocitraturia (>150 mg/day) 30 mEq/day (10 mEq tid).
Administration
Should be taken with food.
Contraindications
Patients w/ hyperkalemia; cardiac arrest; chronic renal failure, uncontrolled DM, acute dehydration, strenuous physical exercise in unconditioned individuals, adrenal insufficiency, extensive tissue breakdown. Patients suffering from delayed gastric emptying, esophageal compression, intestinal obstruction or stricture. Patients w/ PUD; renal insufficiency (GFR of <0.7 mL/kg/min). Concomitant use of K-sparing agent (eg, triamterene, spironolactone or amiloride); anticholinergic medication.
Special Precautions
Potentially fatal hyperkalemia can develop rapidly & be asymptomatic. Patients w/ chronic renal failure, severe myocardial damage or heart failure. Discontinue if severe vomiting, abdominal pain or GI bleeding & possibility of bowel perforation or obstruction investigated. Patients who are taking both diuretics & digitalis prep; w/ trouble swallowing tab or seem to stick in the throat; experience tarry stools or other evidence of GI bleeding.
Adverse Reactions
GI disturbances eg, abdominal discomfort, vomiting, diarrhea, loose bowel movements or nausea.
Drug Interactions
May cause severe hyperkalemia w/ K-sparing diuretic (eg, triamterene, spironolactone or amiloride).
MIMS Class
Other Drugs Acting on the Genito-Urinary System
ATC Classification
A12BA02 - potassium citrate ; Belongs to the class of potassium-containing preparations. Used as dietary supplements.
Presentation/Packing
Form
Positate ER tab 1080 mg
Packing/Price
30's
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