Prazitam 4.5

Prazitam 4.5

piperacillin + tazobactam


Stallion Labs


Clearvue Pharma


Concise Prescribing Info
Piperacillin Na 4 g, tazobactam Na 500 mg
For documented multidrug-resistant gm -ve infections due to organisms proven or suspected to be susceptible to piperacillin/tazobactam except CNS infections & for polymicrobial infections (eg, mixed aerobic & anaerobic infections) in which other agents have insufficient activity or are contraindicated due to toxic potential.
Dosage/Direction for Use
IV infusion over 30 min. IM/IV Adult 3.375 g daily every 6 hr. Total daily dose: 13.5 g. Nosocomial pneumonia Initially 16 g/2 g daily for 7-14 days. Continue aminoglycoside to patients from whom P. aeruginosa is isolated. Community-acquired pneumonia, intra-abdominal, uncomplicated & complicated skin & skin structure infections, pelvic inflammatory disease Childn ≥40 kg 3.375 g every 6 hr + aminoglycoside, ≥9 mth up to 40 kg 100 mg/12.5 mg/kg every 8 hr, 2-9 mth 80 mg/10 mg/kg every 8 hr. Duration of treatment: 7-10 days. Haemodialysis All indications Max: 2.25 g every 12 hr. Nosocomial pneumonia 2.25 g every 8 hr. Additional dose of 0.75 g Prazitam should be administered following each dialysis period on haemodialysis days; no additional dosage for CAPD patients.
Hypersensitivity to penicillins, cephalosporins, β-lactamase antibiotics or β-lactamase inhibitors.
Special Precautions
Allergies to medicines, food or other substances. Cystic fibrosis, bowel inflammation, bleeding problems, CHF or kidney problem. Patients on dialysis or w/ history of severe diarrhea or bowel problems due to an antibiotics. Salt-restricted diet or have low blood K levels. Concomitant use of other medicines, herbal prep or dietary supplement. Pregnancy & lactation.
Adverse Reactions
Agitation; constipation; diarrhea; dizziness; headache; indigestion; nausea; pain; swelling or redness at the inj site; sleeplessness; vomiting. Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody stools; chest pain; decreased urination; depression; fainting; fast, slow, or irregular heartbeat; fever, chills, or sore throat; hallucination; inflammation at the inj site; prolonged muscle relaxation; red, swollen, or blistered skin; seizure; severe diarrhea, vomiting, or stomach pain; shortness of breath; swelling of the hands, ankles or feet; tremor; unusual tiredness or weakness: vag irritation or discharge; vein inflammation or tenderness; yellowing of the eyes or skin.
MIMS Class
ATC Classification
J01CR05 - piperacillin and beta-lactamase inhibitor ; Belongs to the class of penicillin combinations, including beta-lactamase inhibitors. Used in the systemic treatment of infections.
Prazitam-4.5 powd for inj
(+ 10 mL amp diluent ) 1's
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