Prazitam 4.5

Prazitam 4.5 Mechanism of Action

piperacillin + tazobactam

Manufacturer:

Stallion Labs

Distributor:

Clearvue Pharma

Marketer:

Ambica
Full Prescribing Info
Action
Pharmacology: Pharmacokinetics: Both Piperacillin and Tazobactam are not well absorbed in the GIT but have a good bioavailability after an IM injection. They are both widely distributed into different body compartments but penetration into the meninges of Tazobactam is poor when meninges are inflamed. Tazobactam is metabolized to a single inactive metabolite while Piperacillin is metabolized to the desethyl metabolite, which has minor activity. Approximately 68% and 80% of an administered dose of Piperacillin and Tazobactam, respectively are excreted unchanged in the urine.
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Sign up for free
Already a member? Sign in