Prolix

Prolix

prednisone

Manufacturer:

Lloyd

Distributor:

PNSV Asia
Concise Prescribing Info
Contents
Prednisone
Indications/Uses
Endocrine, nervous, CV, renal (eg, nephrotic syndrome), GI, skin & integumentary systems, ocular & resp system of inflammatory & allergic origin (eg, bronchial asthma & skin allergies). Susp: Rheumatic, collagen, neoplastic, hematologic & autoimmune disorders eg, autoimmune hemolytic anemia, idiopathic thrombocytopenic purpura, inflammatory bowel diseases, SLE & some case of Hashimoto's thyroiditis.
Dosage/Direction for Use
5-60 mg daily in divided doses or as a single daily morning dose or as a double dose on alternate days. Tab Immunosuppressive 10-100 mg daily. Primary & secondary adrenocortical insufficiency 5-25 mg daily in divided doses. Adrenogenital syndromes 10-20 mg/m2 daily in divided doses.
Administration
Should be taken with food.
Contraindications
Systemic fungal infections, glaucoma, gastric & duodenal ulcers, certain viral infections & severe psychoneuroses.
Special Precautions
Heart disease, HTN, renal dysfunction, peptic ulcer, systemic fungal infection, history of psychotic disorders, diabetes, TB, osteoporosis, glaucoma, myasthenia gravis, diverticulitis, colitis & viral diseases like herpes. Monitor adverse effects eg, hyperglycemia, glucosuria, Na retention w/ edema, HTN, osteoporosis & fungal infection in patients receiving high dose or on long-term therapy. Avoid abrupt discontinuation of treatment.
Adverse Reactions
Adrenal suppression; GI distress, nausea, peptic ulcer, behavioral disturbances, fluid & electrolyte imbalance, visual disturbances, growth retardation, skin atrophy, moon face, Cushingoid state, hirsutism & muscle atrophy.
Drug Interactions
Reduced effect w/ anticonvulsants, phenobarb, phenytoin, antihistamines, barbiturates, ephedrine, primidone & rifampicin. May reduce the efficacy of hypoglycemics, diuretics, salicylates & anticholinesterases. Enhanced effect w/ aspirin & estrogen. Cyclosporine.
ATC Classification
H02AB07 - prednisone ; Belongs to the class of glucocorticoids. Used in systemic corticosteroid preparations.
Presentation/Packing
Form
Prolix oral susp 10 mg/5 mL
Packing/Price
60 mL x 1's (P140.34/bottle)
Form
Prolix tab 20 mg
Packing/Price
100's (P750/pack)
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