Protopic should be applied as a thin layer to affected areas of the skin twice daily. Protopic may be used on any part of the body, including face, neck and flexure areas, except on mucous membranes. Protopic should not be applied under occlusion (see Precautions).
Each affected region of the skin should be treated with Protopic until clearance occurs and then treatment should be discontinued. Generally, improvement is seen within 1 week of starting treatment. If no signs of improvement are seen after 2 weeks of treatment, further treatment options should be considered. Protopic can be used for short-term and intermittent long-term treatment.