Provestin

Provestin

medroxyprogesterone

Manufacturer:

LBS

Distributor:

International Apex
Concise Prescribing Info
Contents
Medroxyprogesterone acetate
Indications/Uses
Listed in Dosage.
Dosage/Direction for Use
IM Mild to moderate endometriosis 50 mg wkly or 100 mg 2 wkly. Primary & secondary amenorrhagia 5-10 mg daily for 5-10 days until 2 days before anticipated onset of menstruation. Breast carcinoma 500 mg to 1 g daily twice wkly. Endometrial & renal carcinoma 250 mg-1 g wkly. Prostatic carcinoma 500 mg once/twice wkly. Contraception monotherapy 150 mg 12 wkly, combined therapy 25 mg w/ estradiol cipionate 5 mg mthly.
Contraindications
Thrombophlebitis, thromboembolic disturbances, severe hepatic insufficiency, breast carcinoma, undiagnosed vag bleeding, missed abortion.
Special Precautions
CV or renal impairment, DM, asthma, epilepsy & migraine, other conditions aggravated by fluid retention. Depression, high risk of arterial disease.
Adverse Reactions
GI disturbances, appetite or wt changes, fluid retention, edema, acne, chloasma (melasma), allergic skin rashes, urticaria, mental depression, breast changes/discomfort.
Drug Interactions
Aminoglutethimide.
ATC Classification
G03AC06 - medroxyprogesterone ; Belongs to the class of progestogens. Used as systemic contraceptives.
Presentation/Packing
Form
Provestin susp for inj 50 mg/mL
Packing/Price
3 mL x 10 × 1's
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