Quadriderm

Quadriderm

Manufacturer:

Merck Sharp & Dohme

Distributor:

A. Menarini
Concise Prescribing Info
Contents
Per g Betamethasone valerate 610 mcg (equiv to betamethasone 500 mcg), gentamicin sulfate (equiv to gentamicin 1 mg), tolnaftate 10 mg, clioquinol 10 mg
Indications/Uses
Relief of the inflammatory manifestations of corticosteroid responsive dermatoses when complicated by secondary infection including chronic dermatitis of the extremities, erythrasma, balanoposthitis, herpes zoster, eczematoid dermatitis, contact dermatitis, follicular dermatitis, parakeratosis, paronychia, anal pruritus, intertrigo, impetigo, neurodermatitis, angular stomatitis, photosensitivity dermatitis, lichenified inguinal dermatophytosis & tinea infections (eg, tinea pedis, tinea cruris & tinea corporis).
Dosage/Direction for Use
Apply to the affected area bid-tid. Tinea pedis 2-4 wk therapy may be necessary.
Contraindications
Special Precautions
Not for ophth use. Cross-allergenicity among glycosides. Discontinue if irritation or sensitization develops. Adrenal suppression especially in infants & childn. Increased systemic absorption if extensive body surface areas are treated, especially prolonged time periods or in the presence of dermal disruption. Overgrowth of non-susceptible organisms. Blurred vision or other visual disturbances. May stain cloth due to clioquinol. Pregnancy & lactation.
Adverse Reactions
Erythema, pruritus & skin discoloration.
Drug Interactions
Clioquinol: May interfere w/ thyroid function tests. Can yield a false +ve result in ferric chloride test for phenylketonuria.
ATC Classification
D07CC01 - betamethasone and antibiotics ; Belongs to the class of potent (group III) corticosteroids, in combination with antibiotics. Used in the treatment of dermatological diseases.
Presentation/Packing
Form
Quadriderm cream
Packing/Price
5 g x 1's (P474.15/tube)
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