Quadriderm Mechanism of Action


Merck Sharp & Dohme


A. Menarini
Full Prescribing Info
Pharmacotherapeutic Group: Topical corticosteroid and anti-infectives in combination.
Pharmacology: Pharmacodynamics: Mechanism of Action: Betamethasone, Gentamicin, Tolnaftate, Clioquinol (QUADRIDERM) Cream combines the anti-inflammatory, antipruritic and vasoconstrictive agent betamethasone valerate, the wide-spectrum bactericidal antibiotic gentamicin sulfate, the fungicidal agent tolnaftate and clioquinol, an antibacterial and antifungal agent.
Pharmacodynamic Effects: Bacteria susceptible to gentamicin include sensitive strains of Staphylococcus aureus (coagulase positive, coagulase negative and some penicillinase-producing strains) and the gram-negative bacteria: Pseudomonas aeruginosa, Aerobacter aerogenes, Escherichia coli, Proteus vulgaris and Klebsiella pneumoniae.
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