RiteMED Ascorbic Acid

RiteMED Ascorbic Acid

ascorbic acid




United Lab
Full Prescribing Info
Ascorbic acid.
Syrup: Each 5 mL contains: Ascorbic Acid 100 mg.
Pharmacology: Tablet: Vitamin C is a water-soluble antioxidant. It can quench various reactive oxygen and nitrogen species and thus, protects the body from damaging oxidizing agents.
Vitamin C is a cofactor for enzymes involved in important biological processes including synthesis of collagen, carnitine and neurotransmitters eg, norepinephrine and serotonin. It also facilitates the absorption of iron from the GIT.
Vitamin C is important in the defense against infection by enhancing immune function. It plays an important role in the body's response to stress.
Syrup: Ascorbic acid, a water soluble vitamin, is essential for the synthesis of collagen and intracellular material. Ascorbic acid deficiency develops when dietary intake is inadequate. It is rare in adults, but may occur in infants, alcoholics or elderly. Deficiency leads to the development of a well defined syndrome known as scurvy. Ascorbic acid has been used to acidify urine and has also been tried in the treatment of idiopathic methemoglobinemia and many other disorders but there is a little evidence of beneficial effect.
Pharmacokinetics: Tablet: Vitamin C is absorbed from the intestine via an active transport process that is saturable and dose dependent. At low concentrations in the GIT, active transport predominates while simple diffusion occurs at high concentrations.
Absorption is high (up to 70-90%) at doses of 30-180 mg/day; however, absorption falls to ≤50% with increasing doses >1 g/day.
The plasma half-life of ascorbic acid in humans is 16 days. However, in patients without vitamin C deficiency, excess ascorbate is eliminated rapidly with a half-life of 3.4 hrs.
Vitamin C and its metabolites are excreted primarily in the urine.
Syrup: Ascorbic acid is readily absorbed from the gastrointestinal tract and is widely distributed in the body tissues. It is reported to be about 25% bound to plasma proteins. The amount of ascorbic acid in the body is about 1.5 g. The concentration is higher in leukocytes and platelets than in erythrocytes and plasma. In deficiency states that the concentration in leukocytes declines later at a slower rate, and has been considered to be better criterion for the evaluation of deficiency than the concentration in plasma.
Tablet: A nutritional supplement to help promote wound healing and tissue repair; enhance the immune system, increase resistance against infections and speed up recovery from illness; scavenge reactive oxygen and nitrogen species and protect the body from the harmful effects of these oxidants.
Syrup: For the treatment and prevention of Ascorbic acid deficiency.
Dosage/Direction for Use
Tablet: 1-2 tabs daily by mouth.
Syrup: Human Requirements: A daily intake of about 30 mg to 100 mg ascorbic acid has been recommended for adults. There is however, wide variation in individual requirements. Humans are unable to form their own ascorbic acid and so a dietary source is necessary. Most dietary ascorbic acid is obtained from fruit and vegetables sources; only small amounts are present in milks, and in animal tissues, relatively rich sources include rose hips (rose fruit) black currant, citrus fruits, leafy vegetables, tomatoes, potatoes, and green pepper.
Children and Adults over 12 Years: 5 mL to 10 mL (1 to 2 teaspoonful).
Children 7 to 12 Years: 5 mL (1 teaspoonful), 2 to 6 Years: 2.5 mL (1/2 teaspoonful).
To be taken once a day or as prescribed by the physician.
Tablet: Hypersensitivity to any component of RiteMED Ascorbic acid.
Syrup: This product contains FD&C yellow #5 (Tartrazine) which may cause allergic reactions (including bronchial asthma) in certain susceptible persons.
Special Precautions
Syrup: Should be given with care to patients with hyperoxaluria.
Adverse Reactions
Tablet: None expected at recommended doses.
Syrup: Large doses are reported to cause diarrhea and other gastrointestinal disturbances and are associated with the formation of renal calcium oxalate calculi.
Store at temperatures not exceeding 30°C. Protect from light.
Syrup: Always keep bottle tightly closed.
MIMS Class
Vitamin C
ATC Classification
A11GA01 - ascorbic acid (vit C) ; Belongs to the class of ascorbic acid (vitamin C). Used as dietary supplements.
RiteMED Ascorbic Acid syr 100 mg/5 mL
120 mL x 1's (P95/bottle)
RiteMED Ascorbic Acid tab 500 mg
100's (P2.25/tab, P225/box)
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