Proteinuria; myalgia, myopathy, rhabdomyolysis (rarely); interstitial lung disease (long-term therapy); risk of DM. Patients w/ predisposing factors for myopathy/rhabdomyolysis; history of liver disease; secondary hypercholesterolemia. Report immediately if inexplicable muscle pain, weakness or cramps occur, particularly if associated w/ malaise or fever. Not to be used in patients w/ acute, serious condition suggestive of myopathy or predisposing to development of renal failure secondary to rhabdomyolysis. Perform confirmatory test w/in 5-7 days if creatinine kinase (CK) levels is elevated; discontinue CK levels if markedly elevated (>5x ULN). Require liver function test prior to & 3 mth following treatment. Galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption. Concomitant use w/ gemfibrozil, ciclosporin, nicotinic acid, azoles, PIs & macrolides. Excessive alcohol consumption. Dizziness may occur when driving or operating machines. Asian patients. Pregnancy & lactation. Not recommended for childn <10 yr.