Adverse reactions with suspected relationship to treatment are listed by system organ class as follows. Frequencies are defined as very common (>1/10), common (>1/100, <1/10) and uncommon (>1/1,000, <1/100).
General Disorders and Administration Site Conditions: Very Common: Application site burning and pruritus. Common: Application site warmth, erythema, pain, irritation, paresthesia and rash.
Infections and Infestations: Common: Herpes viral infections [herpes simplex dermatitis (eczema herpeticum), herpes simplex (cold sores), Kaposi's varicelliform eruption].
Skin and Subcutaneous Tissue Disorders: Common: Folliculitis, pruritus. Uncommon: Acne.
Nervous System Disorders: Common: Paresthesias and dysesthesias (hyperesthesia, burning sensation).
Metabolism and Nutrition Disorders: Common: Alcohol intolerance (facial flushing or skin irritation after consumption of an alcoholic beverage).