Roxicef S125/Roxicef S250/Roxicef

Roxicef S125/Roxicef S250/Roxicef

cefuroxime

Manufacturer:

ECE Pharma

Distributor:

ECE Pharma
Concise Prescribing Info
Contents
Roxicef S125/Roxicef S250 Cefuroxime axetil. Roxicef Cefuroxime Na
Indications/Uses
Susceptible infections which include bone & joint infections, bronchitis, gonorrhea, meningitis, otitis media, peritonitis, pharyngitis, sinusitis, skin infections, surgical infections & UTI.
Dosage/Direction for Use
Roxicef S125/Roxicef S250 Childn >2 yr w/ otitis media 250 mg bid or 15 mg/kg bid. Max: 500 mg daily. Childn >3 mth 125 mg bid or 10 mg/kg bid Max: 250 mg daily. Roxicef IM/IV Adult 750 mg-1.5 g 6-8 hrly. Childn 75-150 mg/kg/day in divided doses.
Administration
Should be taken with food.
Contraindications
Special Precautions
Penicillin-sensitive patients, GI disease especially colitis. Monitor kidney function. Prolonged treatment. Pregnancy & lactation. Childn <3 mth.
Adverse Reactions
Roxicef S125/Roxicef S250 Skin rashes, urticarial, eosinophilia, fever, reactions resembling serum sickness & anaphylaxis. Roxicef Pain at IM inj site, thrombophlebitis after IV admin. Pseudomembranous colitis, leukopenia, thrombocytopenia, +ve Coombs' test. Hypersensitivity reactions eg, rash, urticaria & anaphylaxis.
Drug Interactions
Increased nephrotoxicity w/ probenecid, ethacrynic acid, furosemide, gentamycin & vancomycin. Disulfiram-like reaction w/ alcohol ingestion, cephalosporins, methyltetrazole-thiol (MTT) sidechain (eg, cefamandole, cefoperazone, moxalactam & cefotetan). High-dose heparin, oral anticoagulants & other drugs that affect hemostasis. May increase the risk of hemorrhage w/ cephalosporins w/ MTT side chain. Inj: Potent diuretics.
MIMS Class
Cephalosporins
ATC Classification
J01DC02 - cefuroxime ; Belongs to the class of second-generation cephalosporins. Used in the systemic treatment of infections.
Presentation/Packing
Form
Roxicef S125 granules for susp 125 mg/5 mL
Packing/Price
50 mL x 1's
Form
Roxicef S250 granules for susp 250 mg/5 mL
Packing/Price
50 mL x 1's
Form
Roxicef powd for inj 750 mg
Packing/Price
1's (P300/box)
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