Adult Erosive reflux esophagitis
40 mg once daily for 4 wk. Additional 4 wk in patients whom esophagitis has not healed or have persistent symptoms. Long-term management of patients w/ healed esophagitis to prevent relapse
20 mg once daily. Symptomatic treatment of GERD
20 mg once daily in patients w/o esophagitis. Subsequent symptom control can be achieved w/ 20 mg once daily. Eradication of H. pylori-associated ulcers
20 mg in combination w/ amoxicillin 1 g & clarithromycin 500 mg, all bid for 7 days. Healing of gastric ulcers associated w/ NSAID therapy
20 mg once daily for 4-8 wk. Prevention of gastric & duodenal ulcers associated w/ NSAID therapy in patients at risk
20 mg once daily. Zollinger-Ellison syndrome
Initially 40 mg bid. Maintenance: 80-160 mg daily. Doses >80 mg should be given in divided doses as bid.