NEW
Scapho

Scapho

secukinumab

Manufacturer:

Novartis Pharma Stein

Distributor:

Novartis Healthcare
Concise Prescribing Info
Contents
Secukinumab
Indications/Uses
Moderate to severe plaque psoriasis in adults, childn & adolescents 6 yr who are candidates for systemic therapy. Treatment of active psoriatic arthritis in adults, alone or in combination w/ methotrexate (MTX), when the response to previous DMARD therapy has been inadequate. Axial spondyloarthritis (axSPA) w/ or w/o radiographic damage; active ankylosing spondylitis in adults who have responded inadequately to conventional therapy. Adults w/ active non-radiographic axSPA w/ objective signs of inflammation.
Dosage/Direction for Use
SC Plaque psoriasis 300 mg given as 2 inj of 150 mg w/ initial dosing at wk 0, 1, 2, 3, & 4 followed by mthly maintenance dosing. Ped ≥50 kg 150 mg (may be increased to 300 mg); 25-<50 kg 75 mg; <25 kg 75 mg. Each 75 & 150 mg is given 1 SC inj; each 300 mg is given as 2 SC inj of 150 mg. Psoriatic arthritis 150 mg w/ initial dosing at wk 0, 1, 2, 3, & 4 followed by mthly maintenance dosing. Can be increased to 300 mg given as 2 inj of 150 mg based on clinical response. Patient who are anti-TNFα inadequate responders or w/ concomitant moderate to severe plaque psoriasis 300 mg given as 2 inj of 150 mg w/ initial dosing at wk 0, 1, 2, 3, & 4 followed by mthly maintenance dosing. Ankylosing spondylitis 150 mg w/ initial dosing at wk 0, 1, 2, 3, & 4 followed by mthly maintenance dosing. Can be increased to 300 mg given as 2 inj of 150 mg based on clinical response. Non-radiographic axial spondyloarthritis 150 mg w/ initial dosing at wk 0, 1, 2, 3, & 4 followed by mthly maintenance dosing.
Contraindications
Special Precautions
Hypersensitivity. Patients w/ chronic infection or history of recurrent infection. IBD. Do not give concurrently w/ live vaccines. Pregnancy & lactation.
Adverse Reactions
Upper resp tract infections (eg, nasopharyngitis, rhinitis, pharyngitis, sinusitis, tonsillitis). Oral herpes, diarrhea, urticaria, rhinorrhea.
MIMS Class
Disease-Modifying Anti-Rheumatic Drugs (DMARDs) / Immunosuppressants / Psoriasis, Seborrhea & Ichthyosis Preparations
ATC Classification
L04AC10 - secukinumab ; Belongs to the class of interleukin inhibitors. Used as immunosuppressants.
Presentation/Packing
Form
Scapho powd for inj 150 mg
Packing/Price
1's
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Sign up for free
Already a member? Sign in