Selenium sulfide


Generic Medicine Info
Indications and Dosage
Topical/Cutaneous
Dandruff, Seborrhoeic dermatitis
Adult: As 2.5% shampoo or lotion: Massage into wet scalp, leave for 2-3 min then rinse thoroughly. Use twice weekly for 2 weeks, may repeat at less frequent intervals subsequently. As 1% shampoo or lotion: Apply 1-2 times weekly.
Child: 5-14 yr Same as adult dose.

Topical/Cutaneous
Tinea versicolor
Adult: As 2.5% lotion: Apply to affected areas, lather w/ a small amount of water and leave on skin for 10 min, then rinse thoroughly. Repeat procedure once daily for 7 days.
Contraindications
Hypersensitivity. Broken or severely inflamed skin.
Special Precautions
Childn. Pregnancy and lactation.
Adverse Reactions
Skin irritation, esp in the genital areas and skin folds; oily scalp, hair discouloration, hair loss.
Patient Counseling Information
Remove gold, silver and other metallic jewellery prior to use. Avoid use of shampoo w/in 48 hr of applying hair dye, straightening or waving preparations.
Action
Description: Selenium sulfide has antifungal and antiseborrhoeic properties. It is active against Pityrosporum ovale, a yeast-like fungus that is part of the normal flora of the scalp. It also has a cytostatic effect on cells of the epidermis and follicular epithelium, thus reducing corneocyte production.
Chemical Structure

Chemical Structure Image
Selenium sulfide

Source: National Center for Biotechnology Information. PubChem Database. Selenium sulfide, CID=24011, https://pubchem.ncbi.nlm.nih.gov/compound/Selenium-sulfide (accessed on Jan. 23, 2020)

Storage
Store between 20-25°C.
ATC Classification
D01AE13 - selenium sulfide ; Belongs to the class of other antifungals for topical use.
References
Anon. Selenium Sulfide. Lexicomp Online. Hudson, Ohio. Wolters Kluwer Clinical Drug Information, Inc. https://online.lexi.com. Accessed 20/05/2016.

Buckingham R (ed). Selenium Sulfide. Martindale: The Complete Drug Reference [online]. London. Pharmaceutical Press. https://www.medicinescomplete.com. Accessed 20/05/2016.

McEvoy GK, Snow EK, Miller J et al (eds). Selenium Sulfide. AHFS Drug Information (AHFS DI) [online]. American Society of Health-System Pharmacists (ASHP). https://www.medicinescomplete.com. Accessed 20/05/2016.

Selenium Sulfide Lotion (Perrigo New York Inc). DailyMed. Source: U.S. National Library of Medicine. https://dailymed.nlm.nih.gov/dailymed/. Accessed 20/05/2016.

Selenium Sulfide Shampoo (Bi-Coastal Pharma International LLC). DailyMed. Source: U.S. National Library of Medicine. https://dailymed.nlm.nih.gov/dailymed/. Accessed 20/05/2016.

Disclaimer: This information is independently developed by MIMS based on Selenium sulfide from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 MIMS. All rights reserved. Powered by MIMS.com
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