Sensorcaine Plain

Sensorcaine Plain





Concise Prescribing Info
Bupivacaine HCl
Surgical anaesth, post-op analgesia, other therapeutic pain blocks & obstet anaesth, particularly where long-acting anaesth is required. Also for a number of anesth techniques including local infiltration, minor & major nerve blocks, epidural block & arthroscopy.
Dosage/Direction for Use
Adult 400 mg over 24 hr. Surgical operations & post-op analgesia (Local infiltration) ≤30 mL. Ocular surgery (Retrobulbar) 2-4 mL (Peribulbar) 6-10 mL. Pain relief for surgery, post-op & trauma (Intercostal per nerve) 2-3 mL. Post-op analgesia (Interpleural) 20 mL. Surgical operations (Brachial plexus) 30 mL (Sciatic) 10-20 mL (femoral, obturator, lateral cutaneous) 20-30 mL. Surgical operations including caesarean section (Lumbar epidural) 15-30 mL. Surgical operations & post-op pain relief (Caudal epidural) 20-30 mL. Childn 2 mg/kg.
Hypersensitivity to local anaesth of the amide type or to Na metabisulphite in soln containing adrenaline. IV regional anaesth (Bier's block).
Special Precautions
Cardiac arrest or death during epidural anaesth or peripheral nerve blockade. Acute toxicity effects on the central nervous & CV systems. Ventricular arrhythmia/fibrillation, sudden CV collapse & death w/ high systemic conc of bupivacaine. Patients in poor general condition, w/ partial or complete heart block, advanced liver disease or severe renal dysfunction, treated w/ anti-arrhythmic class III (eg, amiodarone). Impaired CV function. Vasoconstriction may aggravate tissue reactions. Chondrolysis. Not indicated for intra-articular continuous infusion. Hypotension. When administered as intra-articular inj, caution is advised when recent major intra-articular trauma is suspected or extensive raw surfaces w/in the joint have been created by the surgical procedure. Patients w/ severe or untreated HTN, poorly controlled hyperthyroidism, ischemic heart disease, heart block, cerebrovascular insufficiency, advanced diabetes & any other pathological condition that might aggravate the effects of adrenaline. Pregnancy (late stage) & lactation. Elderly.
Adverse Reactions
Hypotension; nausea. Paraesthesia, dizziness; bradycardia; HTN; vomiting; urinary retention.
Drug Interactions
Additive systemic effects w/ other local anaesth or agents structurally related to amide-type local anaesth eg, certain anti-arrhythmic (eg, lidocaine & mexiletin). Prolonged HTN w/ TCAs. Severe, persistent HTN & possibly cerebrovascular & cardiac accidents w/ oxytocic drugs. May reduce or reverse the pressor effect w/ neuroleptics eg, phenothiazines. Risk of serious cardiac arrhythmia w/ general anaesth w/ inhalation agents eg, halothane & enflurane. Enhance the pressor effect w/ non-selective β-blockers eg, propranolol.
MIMS Class
Anaesthetics - Local & General
ATC Classification
N01BB01 - bupivacaine ; Belongs to the class of amides. Used as local anesthetics.
Sensorcaine Plain soln for inj 0.5%
10 mL x 1's (P1,898.79/polyamp)
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Sign up for free
Already a member? Sign in