IV General anesth induction
Titrate 20-40 mg every 10 sec. Adult <55 yr
1.5-2.5 mg/kg. Elderly, patient of ASA grade III & IV especially those w/ impaired cardiac function
1 mg/kg. Maintenance: Increments of 25-50 mg by repeated bolus inj or 4-18 mg/kg/hr by continuous infusion. Childn >1 mth
2.5 mg/kg. Maintenance: 9-15 mg/kg/hr by continuous infusion. Duration of use: Childn <3 yr
20 min. Max: 75 min. Adult Sedation during intensive care
0.3-4 mg/kg/hr by continuous infusion. Sedation for diagnostic & surgical procedure
0.5-1 mg/kg over 1-5 min. Maintenance: 1.5-4.5 mg/kg/hr infusion. May be supplemented by 10-20 mg bolus inj.