Stangesic

Stangesic

mefenamic acid

Manufacturer:

GXI

Distributor:

Metro Drug
Concise Prescribing Info
Contents
Mefenamic acid
Indications/Uses
Relief of mild to moderate pain arising from RA (including Still's disease), soft tissue injuries, other painful musculoskeletal conditions, headache, dental pain, post-op pain & dysmenorrhea.
Dosage/Direction for Use
Adult & childn >12 yr Initially 1 tab followed by ½ tab every 8 hr as needed. Not to be given >7 days.
Administration
Should be taken with food: Take w/ or immediately after meals.
Contraindications
Hypersensitivity. Patients who have history of stroke, CVA, heart attack, MI, CABG, uncontrolled HTN & CHF (NYHA II-IV). Active peptic ulcer or inflammatory bowel disease. Hepatic & renal impairment. Cross-sensitivity w/ aspirin & other NSAIDs.
Special Precautions
Impaired renal & liver function. Avoid prolonged treatment for >7 days. Concomitant w/ plasma-protein-binding drugs & anticoagulants. Discontinue treatment if skin rash, diarrhea or other significant GI discomfort occurs. Not recommended during pregnancy & lactation. Not recommended in childn.
Adverse Reactions
Dyspepsia, upper GI discomfort, diarrhea or constipation & abdominal pain. Allergic glomerulonephritis; hemolytic anemia, agranulocytosis, pancytopenia, thrombocytopenia or thrombocytopenic purpura & bone marrow aplasia (on long-term treatment).
Drug Interactions
Interferes w/ the anti-platelet effect of low-dose aspirin. Displaces warfarin from protein-binding sites & may enhance response to oral anticoagulants. Reduced efficacy of diuretics & other antihypertensive drugs, including ACE inhibitors, angiotensin II antagonist & β-blockers. Increased risk of GI ulceration or bleeding w/ corticosteroids. May increase risk of nephrotoxicity w/ cyclosporine & tacrolimus. Changes in the effects of oral hypoglycemic agents. Elevation of plasma lithium & reduction in renal lithium clearance. Increased plasma levels of methotrexate.
ATC Classification
M01AG01 - mefenamic acid ; Belongs to the class of non-steroidal antiinflammatory and antirheumatic products, fenamates.
Presentation/Packing
Form
Stangesic FC tab 500 mg
Packing/Price
100's (P5.55/film-coated tab)
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