Strumazol

Strumazol Side Effects

thiamazole

Manufacturer:

Aspen

Distributor:

Zuellig
Full Prescribing Info
Side Effects
The most common minor adverse effects are nausea, vomiting, gastric discomfort, headache, hair loss has also been reported. Bone marrow depression may occur. Full blood counts should be performed. These side effects are usually benign and generally of short duration and occur in approximately 5% of users. In most cases, there is no reason to stop the medication. The signs which may occur, particularly at high doses of Strumazol, are fever, arthralgia, arthritis and rashes (eg, urticaria). Mild rashes usually disappear despite continuation of treatment.
The blood frequently exhibits (transient) leukopenia (<4 x 10/L) which is mostly symptom-free. The frequency is thought to be approximately 10-20% in which it should be noted that mild forms of Graves' disease can also be accompanied by leukopenia. If the number of granulocytes is <1 x 10/L, treatment with Strumazol should be discontinued.
The serious side effect of agranulocytosis is usually characterized by general symptoms eg, fever and bacterial infection. These phenomena are usually acute and often occur within 2-3 months of starting treatment with Strumazol. Patients should be instructed to watch out for and report to their physicians, the occurrence of signs and symptoms eg, fever, sore throat and nose bleeding. Another serious side effect which is sometimes observed is hepatotoxicity, manifesting itself in cholestatic jaundice without liver cell necrosis.
Another rare complication is the occurrence of vasculitis or lupus erythematosus (LE) syndrome. Side effects which very rarely occur are aplastic anemia, thrombocytopenia, nephrotic syndrome and a loss of the sense of taste. Naturally, if Strumazol is administered as monotherapy, it can lead to primary hypothyroidism. After a reduction in thyroid function, Strumazol can also lead to enlargement of the thyroid gland with mechanical difficulties as a possible ultimate complication.
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