Sulbacin Drug Interactions

ampicillin + sulbactam


Singapore Pharmawealth Lifesciences


Phil Pharmawealth


Phil Pharmawealth
Full Prescribing Info
Drug Interactions
Allopurinol: An increased frequency of skin rashes has been reported in patients receiving ampicillin or amoxicillin, with allopurinol, compared with those receiving the antibacterial alone, but this could not be confirmed in a subsequent study.
Chloroquine: The absorption of ampicillin has been reduced in healthy subjects taking chloroquine.
Probenecid prolongs the half-life of ampicillin/sulbactam by competing with it for renal tubular secretion and may be used therapeutically for this purpose.
The possibility of prolonged bleeding time after oral treatment with a broad-spectrum drug like ampicillin should be borne in mind in patients receiving anticoagulants.
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