Reproduction studies in animals revealed no evidence of impaired fertility or harm to the fetus due to this drug. The safety during pregnancy has not been established therefore the drug should not be administered to pregnant patients or women suspected of being pregnant. Therefore use this drug only if the expected therapeutic benefit is thought to outweigh any possible risk.
Low concentration of ampicillin and sulbactam are excreted in the milk. Therefore, caution should be exercised when this drug is administered to a nursing woman.