Tapcom-S

Tapcom-S

Manufacturer:

Santen

Distributor:

Metro Drug
Concise Prescribing Info
Contents
Tafluprost 15 mcg, timolol maleate 5 mg
Indications/Uses
Reduction of IOP in adult patients w/ open-angle glaucoma or ocular HTN who are insufficiently responsive to topical monotherapy w/ β-blockers or prostaglandin analogues & require a combination therapy, & who would benefit from preservative-free eye drops.
Dosage/Direction for Use
1 eye drop in the conjunctival sac of the affected eye(s) once daily.
Contraindications
Hypersensitivity. Reactive airway disease including bronchial asthma, or history of bronchial asthma, severe COPD; sinus bradycardia, sick sinus syndrome, including SA block, 2nd or 3rd degree AV block not controlled w/ pace-maker; overt cardiac failure, cardiogenic shock.
Special Precautions
CV diseases (eg, CHD, Prinzmetal's angina & cardiac failure) & hypotension. Patients w/ 1st degree heart block, severe peripheral circulatory disturbance/disorders (ie, severe forms of Raynaud's disease or syndrome), mild/moderate COPD, subject to spontaneous hypoglycaemia or w/ labile diabetes, angle-closure glaucoma, history of atopy or severe anaphylactic reaction. May mask signs of hyperthyroidism. Choroidal detachment. May block systemic β-agonist effect eg, adrenaline. Possibility of eyelash growth, darkening of eyelid skin & increased iris pigmentation. Aphakic or pseudophakic patients w/ torn posterior lens capsule or anterior chamber lenses, or in patients w/ known risk factors for cystoid macular oedema or iritis/uveitis. Childn & adolescent <18 yr. Do not use during pregnancy & lactation.
Adverse Reactions
Conjunctival/ocular hyperemia, eye pruritus, eye pain, change of eyelashes (increased length, thickness & number), eyelash discolouration, eye irritation, foreign body sensation in eyes, blurred vision, photophobia.
Drug Interactions
Potential additive effects resulting in hypotension &/or marked bradycardia w/ oral Ca channel blockers, β-adrenergic blockers, antiarrhythmics (including amiodarone), digitalis glycoside, parasympathomimetics, guanethidine. May exacerbate rebound HTN which can follow w/drawal of clonidine w/ oral β-blockers. Potentiated systemic β-blockade w/ CYP2D6 inhibitors (eg, quinidine, fluoxetine, paroxetine) & timolol. Mydriasis may result from concomitant use of adrenaline (epinephrine).
MIMS Class
Antiglaucoma Preparations
ATC Classification
S01ED51 - timolol, combinations ; Belongs to the class of beta blocking agents. Used in the treatment of glaucoma.
Presentation/Packing
Form
Tapcom-S ophth soln
Packing/Price
0.3 mL x 30 × 1's
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