Tianeptine


Generic Medicine Info
Indications and Dosage
Oral
Depression
Adult: 12.5 mg tid.
Elderly: Dose reduction to total daily dose of 25 mg.
Renal Impairment
Reduce total daily dose to 25 mg/day.
Administration
Should be taken on an empty stomach. Take before main meals.
Contraindications
Childn <15 yrs. Pregnancy and lactation.
Special Precautions
General anaesthesia; tasks requiring mental alertness. Avoid abrupt withdrawal, dosage to be decreased gradually over 7-14 days.
Adverse Reactions
Abdominal pain, fatigue, nausea, constipation, lack of appetite, insomnia, drowsiness, palpitations, muscular or joint pain, headache, vertigo, tremour, dry mouth, hepatitis (rare)
Overdosage
Gastric lavage followed by symptomatic treatment and monitoring of CV, respiratory, metabolic and renal function.
Drug Interactions
Potentially Fatal: Avoid concurrent admin with MAOI, start tianeptine 2 wk after discontinuation from MAOI.
Food Interaction
Decreased absorption with alcohol.
Action
Description: Tianeptine exerts its antidepressant action by increasing the presynaptic re-uptake of serotonin.
Storage
Store below 30°C.
MIMS Class
Disclaimer: This information is independently developed by MIMS based on Tianeptine from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 MIMS. All rights reserved. Powered by MIMS.com
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