Acute alcohol intoxication, convulsive disorders, patients w/ head injury, shock, reduced level of consciousness of uncertain origin, increased intracranial pressure. Impaired resp function or those receiving medicinal products which can cause resp depression. Monitor patient w/ liver function disorders. Increased possibility of opioid reactions in febrile patients or w/ increased skin temperature. May impair ability to drive & operate machinery. Lactation. Childn <18 yr.