Tri-Alzor

Tri-Alzor

Manufacturer:

Ajanta Pharma Phil

Distributor:

Metro Drug
Concise Prescribing Info
Contents
Per 20 mg/5 mg/12.5 mg tab Olmesartan medoxomil 20 mg, amlodipine besilate 5 mg, hydrochlorothiazide 12.5 mg. Per 40 mg/5 mg/12.5 mg tab Olmesartan medoxomil 40 mg, amlodipine besilate 5 mg, hydrochlorothiazide 12.5 mg. Per 40 mg/10 mg/12.5 mg tab Olmesartan medoxomil 40 mg, amlodipine besilate 10 mg, hydrochlorothiazide 12.5 mg
Dosage/Direction for Use
Administration
May be taken with or without food.
Contraindications
Hypersensitivity to olmesartan medoxomil, amlodipine besilate, hydrochlorothiazide & to other sulfonamide-derived drugs. Patients w/ anuria.
Special Precautions
Hypotension in vol- & salt-depleted patients; severe aortic stenosis; severe obstructive CAD; CHF; renal & hepatic impairment. History of allergy or bronchial asthma. Activation of SLE. Concomitant use w/ lithium. May affect lab test results. Pregnancy & lactation. Elderly.
Adverse Reactions
Hypotension, orthostatic hypotension, rash, pruritus, palpitation, urinary frequency & nocturia. Headache, edema, gynecomastia, jaundice & hepatic enzyme elevations; dizziness, asthenia, angioedema, vomiting, rhabdomyolysis, acute renal failure, alopecia, pruritus, urticaria; electrolyte imbalance.
Drug Interactions
Reduced effects w/ NSAIDs. Potentiation of orthostatic hypotension may occur w/ alcohol, barbiturates or narcotics. Antidiabetic drugs. Additive effect or potentiation w/ other antihypertensive drugs. Reduced absorption of hydrochlorothiazide w/ cholestyramine & colestipol resins. Intensified electrolyte depletion particularly hypokalemia w/ corticosteroids, ACTH. Increased responsiveness to nondepolarizing skeletal muscle relaxants (eg, tubocurarine). Reduced renal clearance of lithium by diuretics.
MIMS Class
Angiotensin II Antagonists / Calcium Antagonists / Diuretics
ATC Classification
C09DX03 - olmesartan medoxomil, amlodipine and hydrochlorothiazide ; Belongs to the class of angiotensin II receptor blockers (ARBs), other combinations. Used in the treatment of cardiovascular disease.
Presentation/Packing
Form
Tri-Alzor 20 mg/5 mg/12.5 mg FC tab
Packing/Price
30's
Form
Tri-Alzor 40 mg/10 mg/12.5 mg FC tab
Packing/Price
30's
Form
Tri-Alzor 40 mg/5 mg/12.5 mg FC tab
Packing/Price
30's
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