Directions for Use: Intramuscular Injection: IM injections of Sterile Ceftriaxone Sodium are prepared by adding 0.9, 1.8, 3.6 mL of sterile water for injection, 0.9% sodium chloride injection, 5% dextrose injection, bacteriostatic water for injection containing 0.9% benzyl alcohol or 1% lidocaine hydrochloride to vials labeled containing 250 mg, 500 mg, 1 g of Sterile Ceftriaxone Sodium respectively to provide solutions containing 250 mg/mL. More dilute solutions of the drug maybe used for IM injection if required.
Intermittent IV infusion: For intermittent IV infusion, vials labeled as containing 250 mg, 500 mg or 1 g of Sterile Ceftriaxone Sodium should be reconstituted with 3.5 (not less than 2.4), 4.8 or 9.6 mL respectively to provide solutions containing approximately 100 mg/mL. Reconstituted solutions of the drug should then be further diluted in compatible IV solution, generally to a concentration of 10-40 mg/mL, although lower concentrations may be used if desired.
Direction for Reconstitution: With 10 mL diluent. Add 3 mL for IM and 10 mL for IV use of Sterile Water for injection.