For OSTEOARTHRITIS the recommended dose is 200 mg daily given by mouth as a single dose or in 2 divided doses.
FOR RHEUMATOID ARTHRITIS the dose is 100 to 200 mg given twice daily. In elderly patients and those of Afro-Carribbean origin treatment should be initiated at the lowest recommended dose.
In the treatment of PAIN and DYSMENORRHEA, an initial dose of 400 mg followed by an additional dose of 200 mg, if necessary, is recommended on the first day, thereafter the dose is 200 mg twice daily.
Treatment for FAP is 40 mg twice daily.
Doses for Osteoarthritis or Rheumatoid Arthritis may be given with or without meals. But for Familial Adenomatous Polyposis, it should be taken with meals.
Or as prescribed by physician.