Ultracaine Heavy

Ultracaine Heavy

Manufacturer:

Jayson Pharma

Distributor:

Macropharma Corp

Marketer:

AGlobal Care
Concise Prescribing Info
Contents
Per mL Bupivacaine HCl 0.5% in dextrose 8%
Indications/Uses
Intrathecal spinal anesth in adult & childn of all ages.
Dosage/Direction for Use
Adult & childn >12 yr Urological 1.5-3 mL or 7.5-15 mg for 2-3 hr infusion. Lower abdominal surgery (including cesarean section), lower limb, including hip surgery 2-4 mL or 10-20 mg for 1.5-3 hr infusion. Pregnant women 2-2.5 mL (10-12.5 mg). Neonate, infant & childn 15-40 kg 0.25-0.3 mg/kg, 5-15 kg 0.3-0.4 mg/kg, <5 kg 0.4-0.5 mg/kg.
Contraindications
Hypersensitivity to bupivacaine HCl & local anesth of amide type. Not to be injected into inflamed or infected areas. Active disease of the CNS eg, meningitis, poliomyelitis, intracranial hemorrhage, sub-acute combined degeneration of the cord due to pernicious anemia & cerebral/spinal tumors; raised intracranial pressure; spinal stenosis & active disease (eg, spondylitis, tumor, TB of the spine) or recent trauma (eg, fracture) in the vertebral column; septicemia; pyogenic infection of the skin at or adjacent to the site of lumbar puncture; cardiogenic/hypovolemic shock; coagulation disorders or ongoing anticoagulation treatment.
Special Precautions
Carefully & constantly monitor CV & resp vital signs & state of consciousness; level of anesth; ECG in patients treated w/ anti-arrhythmic drugs class III (eg, amiodarone). May cause acute toxicity effects on CNS & CVS. Ventricular arrhythmia/fibrillation, sudden CV collapse & death w/ high systemic conc. Increased risk of high or total spinal blockade in elderly & in late stages of pregnancy. Hypotension & bradycardia. Massive ascites, large abdominal tumors or late pregnancy; cardiac decompensation; hypovolemia. Intercostal paralysis; resp embarrassment in patients w/ pleural effusions. Increased risk of intraspinal abscess formation in the post-op period w/ septicemia. Ageing or other compromising factors eg, partial or complete heart conduction block, advanced liver or renal dysfunction. CV & resp depression. Neurological disorders eg, multiple sclerosis, hemiplegia, paraplegia & neuromuscular disorders. Pregnancy. Elderly.
Adverse Reactions
Hypotension, bradycardia; nausea. Postdural puncture headache; vomiting; urinary retention & incontinence.
Drug Interactions
Additive systemic toxic effects w/ other local anesth or amide-type or structurally related local anesth including anti-arrhythmics (eg, lidocaine & mexiletine). Anti-arrhythmic drugs class III (eg, amiodarone).
MIMS Class
Anaesthetics - Local & General
ATC Classification
N01BB51 - bupivacaine, combinations ; Belongs to the class of amides. Used as local anesthetics.
Presentation/Packing
Form
Ultracaine Heavy soln for inj
Packing/Price
4 mL x 10 × 1's
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