Although mometasone furoate is generally well tolerated, skin reactions may occur. The most common adverse events of topical mometasone furoate were burning sensation, pruritus (itching), and skin atrophy or skin thinning. Signs of skin thinning (e.g., shininess of the skin, stretchmarks, "spider veins" or enlarged blood vessels near skin surface) also occurred.
Infections and infestations:
Bacterial skin infections, folliculitis (inflammation of hair follicles), infections, moniliasis (candida infections), secondary infection.
Immune system disorders:
Allergic contact dermatitis (skin inflammation caused by allergy from materials or substances in contact with the skin), worsening of allergy.
Adrenal suppression, cushingoid features (e.g., moon face), Cushing's syndrome, hypothalamic-pituitary-adrenal (HPA) axis disorder, reversible HPA axis suppression, unspecified endocrine disorders.
Metabolism and nutrition disorders:
Hyperglycemia (increased blood sugar level), obesity.
Nervous system disorders:
Bulging fontanel, headache, hyperesthesia (increased sense of touch or sensation), hypoesthesia (reduced sense of touch or sensation), intracranial hypertensio (increased pressure around the brain), paresthesia (tingling or numbness).
Bilateral papilledema (swelling of optic disc in both eyes), cataract, glaucoma.
Ecchymoses (capillary brittleness), hypertension, purpura (reddish purple discoloration in the skin).
Dry mouth, nausea.
Skin and subcutaneous tissue disorders:
Acne, acneiform eruptions, alopecia (hair loss), blister, bruising, dermatitis (inflammation of the skin), dry skin, erythema (abnormal redness of the skin or mucous membranes), furunculosis, hyperpigmentation (darkening of the skin), hypertrichosis (excessive hair growth), hypopigmentation (lightening of the skin), increased size of lesions, loss of skin elasticity, maceration of the skin (softening of skin as a result of prolonged exposure to moisture), miliaria (prickly heat or sweat rash), papule (solid, raised spots on the skin), perioral dermatitis (inflammation of the skin around the mouth), pustular psoriasis, pustule (small collection of pus in the top layer of skin), rosacea (skin condition where parts or the entire face are unusually red, with or without tine visible blood, bumps, or pus-filled bumps), skin depigmentation (loss of color or markings on the skin), skin irritation, unspecified skin disorder, urticaria (hives).
Musculoskeletal and connective tissue disorder:
Growth retardation (in children), osteoporosis.
Renal and urinary disorders:
Glycosuria (glucose in the urine).
Reproductive system and breast disorders:
General disorders and administration site conditions:
Application site pain, application site reactions, steroid withdrawal syndrome, stinging, worsening of disease.
Decreased glucocorticoid levels, delayed weight gain (in children), increased weight.