Vaccine, poliomyelitis

Generic Medicine Info
Indications and Dosage
Intramuscular, Subcutaneous
Active immunisation against poliomyelitis
Adult: As inactivated trivalent vaccine of polio virus types 1,2,3: Primary immunisation: 3 doses of 0.5 mL, given via IM or SC inj at least 8 weeks apart. Booster dose of 0.5 mL is given every 10 years for patient with increased risk of exposure.
Child: As inactivated trivalent vaccine of polio virus types 1,2,3: ≥6 weeks Primary immunisation: Same as adult dose. Booster dose of 0.5 mL is given at 4 years of age.
History of hypersensitivity to any component of the vaccine. Acute febrile illness.
Special Precautions
Patient with immunodeficiency, bleeding disorder/thrombocytopaenia. Postpone vaccination in patients with acute febrile illness. Children. Pregnancy and lactation.
Adverse Reactions
Significant: Inj site reactions (e.g. pain, redness, bruising, swelling, induration), syncope, bleeding, asthenia, fever, hypersensitivity reaction (e.g. anaphylaxis). In children, crying.
Blood and lymphatic system disorders: Lymphadenopathy.
Gastrointestinal disorders: Diarrhoea, nausea, vomiting.
General disorders and administration site conditions: Irritability.
Metabolism and nutrition disorders: Loss of appetite.
Musculoskeletal and connective tissue disorders: Myalgia.
Nervous system disorders: Headache, restlessness.
Skin and subcutaneous tissue disorders: Rash.
Patient Counseling Information
This drug may cause syncope, if affected, do not drive or operate machinery.
Monitoring Parameters
Monitor for hypersensitivity reactions 15 minutes after administration.
Drug Interactions
Increased risk of bleeding with anticoagulants. Decreased immune response with immunosuppressive therapies (e.g. high dose corticosteroids) and immunoglobulin.
Description: Poliovirus vaccine inactivated (IPV) contains poliovirus type 1 (Mahoney strain), type 2 (MEF-1 strain), and type 3 (Saukett strain). It promotes active immunity by inducing production of antibodies against polio virus infection.
Synonyms: Salk vaccine.
Store between 2-8°C. Protect from light. Do not freeze.
Any unused portions should be disposed of in accordance with local requirements.
MIMS Class
Vaccines, Antisera & Immunologicals
ATC Classification
J07BF03 - poliomyelitis, trivalent, inactivated, whole virus ; Belongs to the class of poliomyelitis viral vaccines.
Anon. Poliovirus Vaccine (Inactivated). Lexicomp Online. Hudson, Ohio. Wolters Kluwer Clinical Drug Information, Inc. Accessed 24/07/2018.

Anon. Poliovirus Vaccine Inactivated. AHFS Clinical Drug Information [online]. Bethesda, MD. American Society of Health-System Pharmacists, Inc. Accessed 24/07/2018.

Buckingham R (ed). Poliomyelitis Vaccines. Martindale: The Complete Drug Reference [online]. London. Pharmaceutical Press. Accessed 24/07/2018.

IPOL, Poliovirus Vaccine Inactivated (Sanofi Pasteur Inc.). DailyMed. Source: U.S. National Library of Medicine. Accessed 24/07/2018.

Disclaimer: This information is independently developed by MIMS based on Vaccine, poliomyelitis from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2022 MIMS. All rights reserved. Powered by
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