Valazyd H

Valazyd H

valsartan + hydrochlorothiazide


Cadila Healthcare


Zydus Healthcare Phils
Concise Prescribing Info
Per 160 mg/25 mg FC tab Valsartan 160 mg, hydrochlorothiazide 25 mg. Per 320 mg/12.5 mg FC tab Valsartan 320 mg, hydrochlorothiazide 12.5 mg
Dosage/Direction for Use
Usual starting dose: 160 mg/12.5 mg once daily. Dose may be increased after 1-2 wk of therapy to a max of 320 mg/25 mg once daily as needed.
May be taken with or without food.
Hypersensitivity to valsartan, hydrochlorothiazide or other sulfonamide-derived drugs. Anuria.
Special Precautions
Hypotension in vol- &/or salt-depleted patients. Patients w/ impaired hepatic function or progressive liver disease, biliary obstructive disorders; history of allergy or bronchial asthma; severe CHF, unilateral or bilateral renal artery stenosis. Exacerbation or activation of SLE. Concomitant use w/ lithium. Perform periodic determinations of serum electrolytes at appropriate intervals. Observe for clinical signs of fluid or electrolyte imbalance. Diabetics, postsympathectomy patients. W/hold or discontinue therapy if progressive renal impairment becomes evident. Discontinue before carrying out tests for parathyroid function. Impaired renal function. Pregnancy & lactation. Childn. Elderly.
Drug Interactions
Possible potentiation of orthostatic hypotension w/ alcohol, barbiturates or narcotics. Oral antidiabetic agents & insulin. Additive effect or potentiation w/ other antihypertensives. Reduced absorption w/ cholestyramine & colestipol resins. Intensified electrolyte depletion particularly hypokalemia w/ corticosteroids, ACTH. Possible decreased response to pressor amines (eg, norepinephrine). Possible increased responsiveness to nondepolarizing skeletal muscle relaxants eg, tubocurarine. Risk of lithium toxicity. Reduced diuretic, natriuretic & antihypertensive effect w/ NSAIDs. Risk of symptomatic hyponatremia w/ carbamazepine.
Valazyd H 160 mg/25 mg FC tab
Valazyd H 320 mg/12.5 mg FC tab
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Sign up for free
Already a member? Sign in