Valvex 80/Valvex 160

Valvex 80/Valvex 160



Vexxa Lifesciences


VE Pharma
Concise Prescribing Info
Dosage/Direction for Use
HTN Initially 80 mg once daily, may be increased to 160 mg once daily. Max: 320 mg once daily. Childn 6-18 yr weighing <35 kg Initially 40 mg once daily; ≥35 kg 80 mg once daily. Recent MI Initially 20 mg bid, started as early as 12 hr after MI. Max: 160 mg bid. Heart failure Starting dose: 40 mg bid, up-titrated to 80 & 160 mg bid. Max: 320 mg daily in divided doses.
May be taken with or without food.
Hypersensitivity. Severe hepatic impairment, biliary cirrhosis & cholestasis. Pregnancy (2nd & 3rd trimester).
Special Precautions
Hyperkalemia. Risk of hypotension in Na &/or vol-depleted patients; bilateral renal artery stenosis, primary hyperaldosteronism; aortic or mitral stenosis or hypertrophic obstructive cardiomyopathy; kidney transplantation. Initiation of therapy to patients w/ heart failure or post-MI; triple combination w/ an ACE inhibitor, β-blocker; risk of renal function impairment in patients w/ severe heart failure. Monitor K levels & renal function. Discontinue if angioedema occurs. Renal & mild to moderate hepatic impairment. Childn.
Adverse Reactions
Dizziness or postural dizziness, hypotension or orthostatic hypotension, renal failure & impairment.
Drug Interactions
May increase lithium conc & toxicity. Increased serum K levels w/ K-sparing diuretics, K supplements, salt substitutes containing K. Attenuated antihypertensive effect w/ NSAIDs, selective COX-2 inhibitors.
ATC Classification
C09CA03 - valsartan ; Belongs to the class of angiotensin II receptor blockers (ARBs). Used in the treatment of cardiovascular disease.
Valvex 160 FC tab 160 mg
Valvex 80 film-coated tab 80 mg
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