Vastarel OD

Vastarel OD

trimetazidine

Manufacturer:

Servier

Distributor:

Zuellig
Concise Prescribing Info
Contents
Trimetazidine diHCl
Indications/Uses
Add-on therapy for the symptomatic treatment of patients w/ stable angina pectoris who are inadequately controlled by or intolerant to 1st-line antianginal therapies.
Dosage/Direction for Use
1 cap once daily during breakfast. Patient w/ moderate renal impairment (CrCl 30-60 mL/min) Reduce dose by ½ ie, 1 tab of 35 mg MR tab in the morning during breakfast. Dose titration in elderly should be exercised w/ caution.
Administration
Should be taken with food: Swallow whole, do not open cap.
Contraindications
Hypersensitivity. Parkinson disease, parkinsonian symptoms, tremors, restless leg syndrome & other related movement disorders. Severe renal impairment (CrCl <30 mL/min).
Special Precautions
Not a curative treatment for angina attacks nor as initial treatment for unstable angina or MI, nor in pre-hospital phase or during the 1st days of hospitalization. Can cause or worsen parkinsonian symptoms (tremor, akinesia, hypertonia) especially in elderly. W/drawal of use when movement disorders eg, parkinsonian symptoms, restless leg syndrome, tremors, gait instability occurs (low incidence & usually reversible after discontinuation). Falls may occur, related to gait instability or hypotension, in particular in patients taking antihypertensive treatment. Moderate renal impairment. Patients w/ problems of fructose intolerance, glucose-galactose malabsorption or sucrose-isomaltase insufficiency. May affect ability to drive & use machines. Pregnancy & lactation. Childn <18 yr. Elderly >75 yr.
Adverse Reactions
Dizziness, headache. Abdominal pain, diarrhea, dyspepsia, nausea & vomiting. Rash, pruritus, urticaria. Asthenia.
MIMS Class
ATC Classification
C01EB15 - trimetazidine ; Belongs to the class of other cardiac preparations.
Presentation/Packing
Form
Vastarel OD PR cap 80 mg
Packing/Price
30's
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