IV/IMResp tract & soft tissue infectionsPatients weighing ≥40 kg 250-500 mg every 6 hr, <40 kg 25-50 mg/kg daily in equally divided doses every 6-8 hr. GI or GUT infectionsPatients weighing ≥40 kg 500 mg every 6 hr, <40 kg 50 mg/kg daily in equally divided doses every 6-8 hr. GonorrheaAdult 500 mg for 2 doses every 8-12 hr.Adult & childn Bacterial meningitis 150-300 mg/kg daily in equally divided doses every 3-4 hr. Septicemia 150-200 mg/kg daily IV for at least 3 days, continue by IM every 3-4 hr.
May decrease efficacy of estrogen-containing OCs, Prolonged bleeding time following treatment w/ coagulants. Antagonism w/ chloramphenicol. Increased frequency of skin rashes w/ allopurinol.
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