Like all medicines, Diosmin + Hesperidin can cause side effects, although not everybody gets them. Diosmin + Hesperidin is usually well tolerated. The following side effects can appear: Common (<1/10, >10/100): Diarrhea, dyspepsia, nausea, vomiting.
Uncommon (<1/100, >1000): Colitis.
Rare (<1/1000, >1/10,000): Dizziness, headache, malaise, rash, pruritus, urticaria.
Frequency Not Known: Isolated face, lip, eyelid edema. Exceptionally, Quincke's edema (rapid swelling of tissues eg, the face, lips, mouth, tongue or throat that may result in breathing difficulty).