Vivelon

Vivelon

clopidogrel

Manufacturer:

ADP Pharma

Distributor:

ADP Pharma
Full Prescribing Info
Contents
Clopidogrel.
Description
Each film-coated tablet contains: Clopidogrel Bisulfate USP equivalent to Clopidogrel 75 mg.
Action
Pharmacology: Pharmacokinetics: Clopidogrel is rapidly but incompletely absorbed following oral administration; absorption appears to be about 50%. It is a prodrug and is extensively metabolised in the liver following absorption, mainly to the inactive carboxylic acid derivative. The active metabolite appears to be a thiol derivatives but has not been identified in plasma. Clopidogrel and the carboxylic acid derivatives are highly protein-bond. Clopidogrel and its metabolites are excreted about equally in the urine.
Indications/Uses
Clopidogrel is an analogue of ticlopidine with similar actions. It is given prophylactically as an alternative to aspirin in patients at risk of thromboembolic disorders such as myocardial infarction, peripheral arterial disease and stroke.
Dosage/Direction for Use
Clopidogrel bisulfate should be given as a single daily dose of 75 mg. Or as prescribed by the physician.
Contraindications
Hypersensitivity to the drug. Severe liver impairment. Active pathological bleeding such as peptic ulcer or intracranial haemorrhage.
Special Precautions
It should not be administered to patients with haematopoietic disorders such as neutropenia or thrombocytopenia, haemorrhagic diathesis or other haemorrhagic disorders associated with prolonged bleeding time, or conditions with an increased risk of bleeding such as gastrointestinal ulcers, acute cerebral haemorrhage, or severe liver dysfunction.
Adverse Reactions
Blood dyscrasias, including neutropenia and thrombotic thrombocytopenic purpura, and haemorrhagic disorders have also occurred.
Storage
Store at temperatures not exceeding 30°C.
ATC Classification
B01AC04 - clopidogrel ; Belongs to the class of platelet aggregation inhibitors excluding heparin. Used in the treatment of thrombosis.
Presentation/Packing
FC tab 75 mg x 30's.
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